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The most common side effects were gastrointestinal and manageable with gradual dose escalation

+ We do not treat patients who are pregnant or breastfeeding, who have a known allergy to any component of the formulation including pineapple-derived bromelain, who have an active skin infection in the treatment area, who have a bleeding disorder or are on certain blood-thinning medications, who have significant liver, kidney or heart disease, or who have a history of keloid scarring

The endometrium of patients with endometriosis shows significant upregulation of miR-21-5p [118]

Vasconcelos SM, Goulart MO, Silva MA, Manfredini V, Benfato Mda S, Rabelo LA, et al

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